Science
Mechanism of Action
This extract precisely supports the skin's microbiome by inhibiting the proliferation of undesirable bacteria, such as Staphylococcus and Streptococcus, while simultaneously fostering the growth of beneficial lactobacillus and bifidobacteria. This rebalanced ecosystem facilitates accelerated skin healing, mitigates redness and irritation, and normalizes sebum production, proving beneficial for managing bacterial and fungal acne. Furthermore, it stimulates cellular renewal through enhanced keratinocyte proliferation and migration, contributing to improved collagen synthesis and overall skin repair. Its intrinsic anti-inflammatory properties make it effective against conditions like acne, rosacea, and general irritation. Comprising peptidoglycan, teichoic acid, proteins, enzymes, peptides, and amino acids, this ingredient delivers comprehensive effects including skin nutrition, anti-aging, repair, antioxidant defense, and deep moisturization. It also provides protective benefits against UV-induced damage and photoaging, aids natural DNA repair mechanisms, and can help to achieve a more uniform skin tone by modulating melanin production.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 An in-vivo study demonstrated a notable 47% reduction in skin redness when utilizing Lactobacillus Ferment Lysate Filtrate at a 5% concentration.
- 02 A lotion containing Lactobacillus Ferment Lysate (as part of VHProbi® Mix R) was shown to significantly improve skin barrier function, reduce transepidermal water loss (TEWL), enhance moisturization, and substantially decline redness in sensitive skin after 30 days.
- 03 A postbiotic cream (pH 6.00 ± 0.02) incorporating Lactobacillus Ferment Lysate yielded clinically significant improvements in atopic dermatitis and reduced recurrence over two- and four-month periods.
- 04 General usage concentrations between 1% and 10% are effectively employed for moisturizing, anti-aging, promoting cell renewal, and supporting collagen production and skin repair.
Transparency
Dusting Analysis
No data indicates that this ingredient is commonly used at sub-efficacious concentrations for marketing purposes. Clinical studies support its benefits at specified percentages.
The Formula
Formulation
Stability
This ingredient maintains stability at temperatures up to 60°C. Optimal storage is recommended at 23-25°C, with an acceptable range between 16°C and 32°C. For optimal integration, it should be introduced into the aqueous phase of formulations, and specifically for emulsions, added post-emulsification once the temperature has cooled below 40°C.
Safety
Safety Profile
The CIR Expert Panel has concluded that Lactobacillus Ferment Lysate and its related derivatives are safe for use in cosmetics. While generally well-tolerated with a low potential for irritation, individuals with particularly sensitive skin are advised to perform a patch test due to its natural, probiotic-derived origin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lactobacillus Ferment Lysate Extract is an essential postbiotic ingredient, offering profound multi-functional benefits including microbiome rebalancing, enhanced barrier function, significant redness reduction, and comprehensive anti-aging properties suitable for all skin types.
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