Science
Mechanism of Action
Operating on a multifaceted level, Lactobacillus Extract Filtrate works to enhance the skin's natural barrier by increasing tight junction protein expression, thereby minimizing transepidermal water loss. It exerts anti-inflammatory and calming effects by modulating the secretion of inflammatory cytokines. This ingredient also plays a crucial role in cultivating a healthy skin microbiome, which in turn reinforces the skin's protective functions, stabilizes its pH, and diminishes irritation. Further benefits include enhanced skin hydration, accelerated recovery from environmental stressors, and robust antioxidant activity to combat free radical damage and mitigate premature aging. In vitro studies indicate its capacity to boost cellular oxygen uptake, stimulate collagen production, and increase ATP synthesis, while also inhibiting pathogenic skin bacteria and supporting optimal cellular turnover.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 An in-vivo study with 5 participants observed a 47% reduction in redness with the application of a similar Lactobacillus ferment lysate filtrate.
- 02 A Lactobacillus extract demonstrated efficacy in reducing bacterial growth on the skin in 6 out of 9 panelists.
- 03 A product containing 5% Lacticaseibacillus rhamnosus lysate filtrate, applied twice daily for 4 weeks, exhibited no irritation in 21 female subjects.
Transparency
Dusting Analysis
Clinical studies demonstrate efficacy at concentrations ranging from 5% to 20%, with typical formulation usage noted between 1% and 10%. This robust evidence confirms that effective concentrations are well-established and routinely incorporated into formulations, indicating a low likelihood of this ingredient being included at ineffectual 'dusting' levels.
The Formula
Formulation
Stability
This ingredient maintains stability at temperatures up to 60°C. Should it change appearance due to cold exposure during shipping or storage, its normal state can be restored by carefully warming to 45-50°C.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Lactobacillus Ferment, Lactobacillus Ferment Filtrate, Lactobacillus Ferment Lysate, and Lactobacillus Ferment Lysate Filtrate are safe for use in cosmetics. While generally non-irritating, there is a low potential for allergic reactions in highly sensitive skin types, necessitating a patch test recommendation. Formulators must exercise caution regarding its potential to inhibit tyrosinase activity, as this skin lightening effect could be classified as a drug claim by regulatory bodies, thus requiring usage in a manner that avoids skin depigmentation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lactobacillus Extract Filtrate is a valuable postbiotic ingredient that comprehensively supports skin health by enhancing barrier function, balancing the microbiome, and delivering soothing and anti-aging benefits across all skin types.
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