Science
Mechanism of Action
The Eriobotrya Japonica component is rich in phenolic compounds, carotenoids, flavonoids, oleanolic acid, and ursolic acid. These act as potent antioxidants by scavenging free radicals and protect skin from oxidative stress. They also exert anti-inflammatory effects by calming responses and inhibiting inflammatory cytokine production, potentially modulating the MAPK signaling pathway. Furthermore, this component demonstrates antimicrobial properties and can help preserve collagen and hyaluronic acid levels by inhibiting collagenase and hyaluronidase enzymes. The Lactobacillus ferment component contributes to a healthy skin microflora through its antimicrobial and anti-inflammatory actions, which may aid in managing conditions like acne and rosacea, and also supports potential DNA repair mechanisms to protect against environmental damage.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Eriobotrya Japonica Leaf Ethanol Extract (EJEE) significantly inhibited nitric oxide (NO) production in stimulated macrophage cells, with 69.24% inhibition at 0.125%. It also showed minor inhibition of TNF-α expression at 0.5% and protected human skin from oxidative stress and inflammation, exhibiting anti-oxidant, anti-inflammatory, and anti-melanogenesis activities.
- 02 Lactobacillus ferment was effective in treating acne by reducing harmful bacteria and fostering a healthy microflora, demonstrating faster results than salicylic acid in reducing acne lesion size and redness.
- 03 Lactobacillus ferment significantly reduced skin sensitivity.
Transparency
Dusting Analysis
No data available to suggest this ingredient is commonly 'dusted' at ineffective concentrations. Clinical findings support efficacy at specific percentages of its components.
The Formula
Formulation
Stability
Ferment filtrates are typically aqueous solutions. The Eriobotrya Japonica Leaf Extract component helps maintain potency and enhances overall stability within a formulation.
Safety
Safety Profile
The CIR Expert Panel deems Lactobacillus Ferment and its filtrates safe for cosmetic use. Eriobotrya Japonica Leaf Extract demonstrated no irritation to skin or eyes in alternative animal tests. The 'Eriobotrya japonica leaves extract' also holds FEMA GRAS (Generally Recognized As Safe) status for food use. The 1.5% maximum concentration is specifically noted for Lactobacillus Ferment in makeup bases.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This dual-fermented ingredient offers a valuable blend of antioxidant, anti-inflammatory, and microbiome-balancing benefits, making it highly compatible across all skin types for targeted treatment and overall skin health.
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References
Sources