Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

LACTOBACILLUS/DENDROPANAX MORBIFERUS SAP FERMENT FILTRATE.

Valuable / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

This ingredient is a ferment filtrate derived from Dendropanax morbiferus sap, produced with Lactobacillus. It offers comprehensive benefits for skin health, including significant anti-hyperpigmentation, anti-inflammatory, and antimicrobial properties.

Summary

Skin conditioning Emollient Anti-hyperpigmentation agent Anti-inflammatory agent Antimicrobial agent Antioxidant Collagen synthesis promoter Skin microflora balancer

Science

Mechanism of Action

This ferment filtrate functions through multiple pathways to enhance skin. Extracts of Dendropanax morbiferus actively reduce hyperpigmentation by inhibiting tyrosinase activity and melanin synthesis. It also exerts anti-inflammatory effects by decreasing nitric oxide (NO) production and suppressing key interleukin markers (ILs), while providing antimicrobial defense against various bacteria and fungi. The ingredient further contributes antioxidant benefits by neutralizing reactive oxygen species (ROS) and supports skin structure by promoting collagen synthesis. Lactobacillus ferments within the ingredient condition the skin, help balance the skin's microflora, and may possess DNA repair and ATP synthesis capabilities, with some postbiotics directly inhibiting tyrosinase for a brightening effect.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Decreased melanin content by inhibiting tyrosinase activity and protein expression of tyrosinase and TRP-2 in vitro.
  2. 02 Showed strong antimicrobial effects against S. epidermidis and S. aureus in vitro.

Transparency

Dusting Analysis

Not commonly dusted

No data available to suggest this ingredient is commonly dusted or to establish a dusting threshold.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Lactobacillus fermentation processes typically yield acidic products, causing a pH decrease during fermentation. When used as a natural preservative, ferment-based ingredients may require complementary preservation strategies, such as pH control or the inclusion of co-preservatives.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
1.5%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Lactobacillus Ferment and its filtrates/lysates safe for cosmetic use. The highest reported concentration of use in leave-on formulations is 1.5% in makeup bases. The panel noted that the skin lightening effect, attributed to tyrosinase inhibition, might be considered a drug effect. Formulators should ensure its use does not lead to unintended skin depigmentation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This ferment filtrate is a valuable multifunctional ingredient, offering robust benefits in brightening, anti-inflammation, antimicrobial protection, and skin conditioning, making it suitable for a wide range of precision skincare formulations.

Related

Similar Ingredients

Finding similar ingredients…