LACTOBACILLUS/DANDELION LEAF/ROOT EXTRACT FERMENT FILTRATE.

The fermentation of dandelion extract by Lactobacillus transforms larger molecules into smaller, more bioavailable components, optimizing skin penetration and efficacy. This ingredient combines the benefits of both Lactobacillus ferment, known for its antimicrobial, anti-inflammatory, and microflora-balancing effects, and dandelion extract. Enhanced by fermentation, the dandelion components provide potent antioxidant activity, scavenging free radicals and mitigating oxidative stress. Specifically, the fermented broth has been shown to fortify the skin barrier by increasing filaggrin (FLG) and aquaporin (AQP3) expression, while reducing kallikrein-7 (KLK-7). It also precisely regulates reactive oxygen species (ROS) and critical inflammatory factors like IL-6, IL-8, IL-1β, and TNF-α by modulating the MAPK pathway, effectively addressing UVB-induced inflammation and cellular senescence.