Science
Mechanism of Action
This ingredient exerts its effects through a dual-pronged mechanism. Lactobacillus fermentation produces a rich filtrate containing beneficial metabolites, enzymes, and peptides that bolster the skin's natural barrier, support a stable skin microbiome, and act as humectants to significantly improve hydration. These ferment byproducts also exhibit potent antioxidant activity, helping to neutralize free radicals and balance skin pH. Notably, certain Lactobacillus metabolites can inhibit tyrosinase, which contributes to reducing hyperpigmentation and enhancing skin brightness. Concurrently, Cudrania tricuspidata bark delivers key phytochemicals like xanthones and flavonoids, known for their anti-inflammatory and antioxidative properties. Research indicates that compounds from Cudrania tricuspidata can decrease pro-inflammatory markers such as IL-6 and IL-8 production and inhibit NF-κB translocation in human keratinocytes, providing targeted soothing and protective action at a cellular level. The combined effect functions comprehensively as an antioxidant and skin conditioning agent.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Lactobacillus Ferment, along with its filtrates and lysates, is safe for use in cosmetics. This ingredient consists of byproducts from Lactobacillus fermentation, including metabolites, enzymes, peptides, organic acids, and bacterial fragments, not live bacteria. It has been reported for use at up to 5.6% in face and neck products. In vitro and human repeated-insult patch tests (HRIPTs) conducted at concentrations up to 100% for filtrates demonstrated that these ingredients are non-irritating and non-sensitizing.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-beneficial ingredient offers comprehensive skin support by strengthening the barrier, enhancing hydration, calming irritation, and promoting an even, radiant complexion, all with a robust safety profile.
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