Science
Mechanism of Action
LACTOBACILLUS/BROCCOLI EXTRACT FERMENT FILTRATE acts multifacetedly on the skin. The Lactobacillus ferment filtrate strengthens the skin barrier, promotes a balanced microbiome by encouraging beneficial bacteria, and calms irritation. It also functions as a humectant, drawing moisture into the skin, and provides antioxidant protection against free radicals and environmental aggressors. Organic acids, such as lactic acid, contribute to maintaining a healthy skin pH and support gentle cellular turnover. The fermented broccoli extract component is shown to boost skin hydration by modulating HAS and NF-κB pathways, and to diminish wrinkle formation via the TGF-βR1/Smad3/Collagen Pathway. It further helps mitigate UVB-induced damage, including moisture loss, oxidative stress, inflammation, and melanin production. Additionally, postbiotics from Lactobacillus fermentation may inhibit tyrosinase activity, offering potential benefits for hyperpigmentation.
Research
Clinical Evidence
Medium confidence3%
Key findings
- 01 Reduced skin redness by 47% in a study involving 5 participants (Lactobacillus Ferment Lysate Filtrate).
- 02 Reduced skin sensitivity (Lactobacillus Ferment).
- 03 Demonstrated anti-acne effects (Lactobacillus Ferment).
- 04 Significantly decreased skin redness and sensitivity in 52 subjects when incorporated into a lotion containing fermented cultures of Lacticaseibacillus rhamnosus and Lactobacillus paracasei.
- 05 Increased antioxidant activity in Caco2 cells and inhibited proliferation of HT29 and HT116 cell lines in a concentration-dependent manner (fermented broccoli extracts, in vitro).
Transparency
Dusting Analysis
This ingredient offers a wide array of scientifically supported benefits at relevant concentrations, making it a valuable active ingredient rather than a 'dusting' component.
The Formula
Formulation
Stability
The Lactobacillus ferment component maintains stability within an aqueous pH range of 4.0-5.0. The natural lactic acid fermentation process inherent to fermented broccoli extracts typically achieves a pH around 3.95-4.0, which contributes to stability and inhibits spoilage microorganisms. For optimal formulation, incorporate directly into aqueous phases at temperatures below 50°C. If utilized for its preservative properties, it should be part of a comprehensive preservation system.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that similar Lactobacillus ferment derivatives are safe for use in cosmetics. The maximum reported concentration for Lactobacillus Ferment is up to 5.6% in face and neck products (non-spray) and other skincare preparations. Formulators should be aware that postbiotics from Lactobacillus fermentation can act as tyrosinase-inhibitors, potentially leading to skin depigmentation if not used judiciously.
Your Skin
Skin Compatibility
Our Assessment
Verdict
LACTOBACILLUS/BROCCOLI EXTRACT FERMENT FILTRATE is a valuable multi-functional ingredient, clinically shown to reduce redness and sensitivity while offering significant hydration, antioxidant protection, and anti-aging benefits across all skin types.
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References
Sources