Science
Mechanism of Action
Operating through multifaceted pathways, Lactic Yeasts function as potent humectants, actively drawing and retaining moisture to significantly boost skin hydration and fortify the natural skin barrier. They stimulate the skin's intrinsic renewal processes, promoting cell turnover and supporting collagen production to diminish fine lines and enhance skin elasticity. As antioxidants, they expertly neutralize free radicals, offering robust protection against environmental damage. Moreover, these ingredients can elevate cellular energy (ATP) production and oxygen uptake within skin cells. Specifically, Lactobacillus ferment lysates are key in nurturing a balanced skin microbiome, modulating immune responses to reduce redness and irritation, and accelerating healing through antimicrobial peptides. They also improve the bioavailability of other active ingredients.
Research
Clinical Evidence
High confidence0.1%-5%
Key findings
- 01 Formulations incorporating Lactobacillus Ferment Lysate effectively decreased transepidermal water loss (TEWL), reduced facial redness, and significantly improved skin hydration.
- 02 A lysate derived from Lactobacillus delbrueckii subsp. bulgaricus LB86, applied in a cream base, markedly increased dermal hydration levels compared to a control formulation.
- 03 A blend of yeast extract and Mannitol (Regenacell™) demonstrated a stimulation of cell growth by up to 47% and an improvement in oxygen uptake by up to 45%.
- 04 Saccharomyces Ferment Filtrate is recommended for use in leave-on products within a concentration range of 0.1% to 5% for optimal efficacy.
Transparency
Dusting Analysis
Lactic Yeasts, specifically Saccharomyces Ferment Filtrate, are recommended at concentrations of 0.1% to 5% for effective use in leave-on skincare products. Formulations claiming benefits from this ingredient at concentrations below 0.1% may be considered under-dosed and potentially insufficient to deliver the full spectrum of advertised benefits.
The Formula
Formulation
Stability
Lactobacillus Ferment Lysate maintains optimal stability when stored between 23-25°C, with a permissible range of 16-32°C, and should not be frozen. While a specific optimal pH for formulated products is not explicitly stated, fermentation processes often occur within a pH range of 3.5-4.5.
Synergies
- Enhances the bioavailability of other active ingredients in a formulation.
Safety
Safety Profile
The Lactobacillus genus is non-pathogenic, and multiple strains of lactic acid bacteria have been tested at 100% concentration, demonstrating no skin or eye irritation. Saccharomyces Ferment Filtrate is recognized as a safe cosmetic ingredient with no reported side effects. A patch test is advisable prior to full usage, particularly when using higher concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lactic Yeasts are a valuable and versatile ingredient, offering significant, scientifically-backed benefits for hydration, barrier integrity, anti-aging, and soothing across all skin types with a low risk of irritation.
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References
Sources
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