Science
Mechanism of Action
LACHANCEA/HYDROLYZED RICE FERMENT FILTRATE operates through multifaceted pathways to enhance skin health. It exhibits powerful antioxidant properties by scavenging free radicals and inhibiting DPPH up to 52%, thereby protecting skin from oxidative stress and premature aging. Its anti-aging effects stem from significantly increased collagen production and stabilization of collagen mRNA via HuR regulation, which helps to reduce the appearance of fine lines, sagging, and uneven texture. The ingredient deeply hydrates the skin by stimulating cell renewal and increasing key proteins such as Aquaporin-3 (AQP3) and Filaggrin (FLG), consequently improving moisture retention and minimizing the visibility of wrinkles. This ferment also fortifies the skin's natural barrier, enhancing its resilience against environmental aggressors. Furthermore, it supports a more even skin tone through potential pigmentation reduction and acts as an anti-inflammatory agent by decreasing the expression of inflammatory markers. It refines skin texture and minimizes pores by stimulating cellular turnover and helps manage acne by regulating sebum production without compromising the skin's natural barrier. The fermentation process breaks down larger molecules, making its rich composition of amino acids, peptides, enzymes, organic acids, polyphenols, polysaccharides, vitamins, and minerals more bioavailable for skin absorption.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Enhanced collagen synthesis by 198% in HFF-1 cells, relative to 0.5% Rice Ferment Filtrate (RFF) alone.
- 02 Significantly increased AQP3 protein content by 28% and FLG protein expression by 26% in human keratinocytes, concurrently boosting skin water content.
- 03 Further increased AQP3 protein content by 71% and FLG protein expression by 51% in human keratinocytes; however, it did not show substantial additional improvement in water content compared to 1.25%.
- 04 Decreased transepidermal water loss (TEWL) by 25.05% after just ten minutes, indicating rapid barrier improvement.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Fermentation processes typically yield stable, pH-balanced formulations. The Lachancea component can produce lactic acid, potentially lowering the formulation's pH by 0.5 units or more. No specific optimal pH range for the stability of the final ingredient was identified.
Synergies
- Sialic acid (demonstrated to significantly boost collagen synthesis when combined with this ferment)
Safety
Safety Profile
The CIR Expert Panel concluded that data for many yeast-derived ingredients, including this specific ferment, were insufficient to make a determination of safety. However, Lactobacillus Ferment Filtrate, a related ferment, has been deemed safe for cosmetic use. Generally, Rice Ferment Filtrate demonstrates a high safety profile and is well-tolerated, with rare reports of allergic reactions; patch testing is advisable for sensitive skin. Cosmetic formulators should ensure that if skin lightening is observed, the ingredient is used in a manner that does not cause undesirable skin depigmentation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
LACHANCEA/HYDROLYZED RICE FERMENT FILTRATE is a valuable, multi-functional ingredient that significantly boosts skin hydration, collagen synthesis, and barrier function while offering antioxidant and soothing properties across various skin types.
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