Science
Mechanism of Action
This ingredient employs a multi-targeted approach, leveraging the distinct benefits of both fermented filtrates and Artemisia princeps. The Kluyveromyces and Lactobacillus ferments actively contribute to enhanced skin conditioning, providing significant antioxidant capabilities and overall skin protection. Fermentation with Lactobacillus is particularly notable for generating bioactive compounds that effectively inhibit the release of inflammatory mediators, such as interleukin-8 (IL-8), thereby reducing skin inflammation. Furthermore, Lactobacillus ferment is recognized for its potential to aid in DNA repair, defend against environmental aggressors, and exhibit antimicrobial properties, fostering a healthy skin microflora beneficial for managing problematic skin conditions. Artemisia princeps extract (mugwort) complements these actions with powerful antioxidant, anti-inflammatory, and moisturizing effects. It works to calm the skin, visibly reduce redness, promote cellular regeneration, and fortify the skin barrier by enhancing the expression of essential proteins like filaggrin and loricrin. Its ability to prevent bacterial proliferation makes it highly advantageous for addressing concerns like acne and rosacea.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A water extract of Artemisia princeps, when fermented with Lactobacillus plantarum SN13T, strongly inhibited the release of interleukin (IL)-8, indicating significant anti-inflammatory effects.
- 02 Lactobacillus Ferment demonstrated effectiveness in reducing skin sensitivity at 1% concentration.
- 03 Lactobacillus Ferment showed anti-acne effects at a 5% concentration.
- 04 Lactobacillus Ferment Lysate Filtrate achieved a 47% reduction in redness at a 5% concentration in a small 5-person in-vivo study.
- 05 Artemisia naphtha oil (not the specific ferment filtrate) at 1% concentration was effective in reducing symptoms of acne and eczema when applied locally for 2 weeks to acne-prone skin.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While the exact combined ingredient lacks a specific CIR assessment, the CIR Expert Panel has deemed its related components, such as Lactobacillus Ferment, Lactobacillus Ferment Filtrate, Lactobacillus Ferment Lysate, and Lactobacillus Ferment Lysate Filtrate, as safe for cosmetic use. Lactobacillus Ferment has been reported in face and neck products at concentrations up to 5.6%. There is no specific safety status for the exact combined ingredient from CIR, SCCS, or FDA, but similar fermented oil filtrates are regulated within the EU.
Your Skin
Skin Compatibility
Our Assessment
Verdict
KLUYVEROMYCES/LACTOBACILLUS/ARTEMISIA PRINCEPS LEAF OIL FERMENT FILTRATE is a valuable ingredient, offering significant anti-inflammatory, antioxidant, and skin barrier-supporting benefits, making it highly beneficial for a wide array of skin types and concerns, including sensitive and problematic skin.
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