Science
Mechanism of Action
Kluyveromyces Extract operates as a skin-conditioning agent and humectant, contributing to enhanced epidermal moisture retention. Its primary action involves the stimulation of collagen synthesis, which effectively addresses both intrinsic (chronobiological) and extrinsic (photo-induced) pathways of skin aging. Additionally, exopolysaccharides derived from related Kluyveromyces species demonstrate notable antioxidant activities, including the scavenging of various free radicals and reduction of oxidative stress.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The parent Kluyveromyces marxianus yeast is highly tolerant to a wide pH range (2.5-9) and temperatures up to 52 °C. While an optimal fermentation pH of 6.7-7 was noted for exopolysaccharide production, specific optimal pH ranges for the stability of the extract in cosmetic formulations are not directly documented.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has acknowledged Kluyveromyces Extract as a skin-conditioning humectant within its yeast-derived ingredients report but has not provided a specific safety assessment conclusion for its use in cosmetic formulations. Oral administration studies in female mice at high concentrations reported statistically significant lower spleen and liver to body ratios in some groups, but no other adverse effects were observed. Comprehensive topical safety data, particularly regarding sensitization potential, for human cosmetic application remains to be thoroughly evaluated.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Kluyveromyces Extract is a valuable active for rejuvenating formulations, offering promising anti-aging benefits through collagen stimulation, potent antioxidant defense, and humectant properties.
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References
Sources