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KEFIRAN.

Valuable / SKIN CONDITIONING

Kefiran is a water-soluble polysaccharide derived from kefir, known for its multifaceted benefits to the skin. It acts as a powerful postbiotic, enhancing the skin's natural defenses, promoting hydration, and contributing to overall skin resilience.

Antioxidant Anti-inflammatory Antimicrobial Wound Healing Moisturizing Skin Barrier Support Elasticity Improvement Firming Collagen Synthesis

Science

Kefiran functions through anti-microbial, anti-inflammatory, and antioxidant pathways, actively supporting skin health. It aids in wound healing by promoting cell adhesion and proliferation, while simultaneously boosting skin hydration by increasing moisture levels and reducing transepidermal water loss (TEWL). Furthermore, Kefiran fortifies the skin barrier against environmental stressors, improves skin elasticity and firmness, and is indicated to enhance collagen synthesis to reduce the appearance of sagging.


Research

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Enhanced wound healing and protective effect on skin connective tissue, observed in an animal study using a 70% kefir gel.
  2. 02 Demonstrated a 9.4% improvement in skin barrier function, utilizing a proprietary kefir active ingredient (CefiraProtect™) in formulation.
  3. 03 Achieved a 7% improvement in skin elasticity, evaluated with a proprietary kefir active ingredient (CefiraProtect™) in formulation.
  4. 04 Showed a significant 16.9% reduction in sagging skin after 28 days of use, with a proprietary kefir active ingredient (CefiraProtect™) in formulation.
  5. 05 Led to a significant reduction in hidden inflammation in 90% of participants when compared to a placebo, using a proprietary kefir active ingredient (CefiraProtect™) in formulation.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Kefiran is a water-soluble polysaccharide, ideally mixed into the water-phase of formulations. It can form films at concentrations between 0.5% and 1% (5-10 g/kg), with glycerol addition improving film flexibility. It is frequently incorporated into vegan, postbiotic formulations.


Safety

CIR Status
Insufficient data
Sensitization risk Low

Kefiran is generally considered safe for human use, with its degradation products classified as GRAS (Generally Recognized As Safe). However, specific safety determinations or maximum concentrations for cosmetic use by the CIR Panel, SCCS, or FDA for Kefiran itself are not explicitly available in reviewed reports.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Kefiran is a valuable postbiotic ingredient offering significant benefits in hydration, barrier function, elasticity, and anti-aging, making it suitable for a wide range of precision skincare applications.


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