Science
Mechanism of Action
This fermented extract functions primarily as a skin conditioning agent and humectant, effectively drawing and retaining moisture to bolster the skin's natural barrier. Its rich content of bioactive compounds, including flavonoids and phenolic acids, provides robust antioxidant protection against environmental stressors and free radicals. The ingredient actively intervenes in glycation processes, protecting structural proteins and reducing Advanced Glycation End-products (AGEs) that contribute to skin yellowing and loss of firmness. Furthermore, it works to inhibit melanin production for a more even and brighter skin tone, while offering anti-aging benefits by promoting collagen synthesis, regulating enzymes like SIRT1 and MMP-1, and defending against UV-induced damage. It also reduces skin irritation by downregulating inflammatory mediators such as IL-6 and IL-8.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Prunus Mume fruit extract protected skin structural proteins against glycation and AGEs decomposition, reducing yellowish pigmentation and improving skin tone and firmness. It has also been clinically tested to enhance skin transparency.
- 02 Prunus Mume extracts demonstrated a skin-whitening effect by inhibiting melanin production through regulation of melanogenesis-associated protein expression in melanocytes.
- 03 An extract of Prunus mume ripened seed (PmRS) was found to be non-toxic on the skin and offered protection against ultraviolet (UV)-induced skin aging in mice. In vitro, PmRS prevented UVB-induced reactive oxygen species in HaCaT cells and modulated key enzymes, downregulating MMP-1 and MMP-13 while upregulating SIRT1 and collagen levels, at concentrations of 10, 30, and 100 μg/ml.
- 04 Fructus Mume extract alleviated skin irritation by inhibiting the secretion of inflammation-related mediators, specifically IL-6 and IL-8.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The specific ingredient 'KAZACHSTANIA/PRUNUS MUME FRUIT EXTRACT FERMENT FILTRATE' has not been directly reviewed by the CIR Expert Panel. However, related ferment filtrates are generally deemed safe. Studies on Prunus Mume extracts indicate low toxicity and no significant cytotoxicity, with ripened seed extract found to be non-toxic on the skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
KAZACHSTANIA/PRUNUS MUME FRUIT EXTRACT FERMENT FILTRATE is a valuable multi-functional ingredient, offering significant benefits for anti-aging, brightening, hydration, and soothing skin, supported by various in-vitro and some clinical studies.
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