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Moumoujus

KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT.

Insufficient Data CAS - / SKIN CONDITIONING

KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT is a botanical ingredient derived from the Kadsura japonica plant. While direct clinical studies on this specific extract are limited, research on related Kadsura species suggests it may confer antioxidant, anti-inflammatory, and skin-brightening benefits, along with photoprotective properties.

Summary

Antioxidant Anti-inflammatory Skin brightening Photoprotective

Science

Mechanism of Action

The proposed mechanism of KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT, inferred from studies on the Kadsura genus and Kadsura coccinea, involves multi-targeted action. Its anti-melanogenic effects are likely achieved by reducing the protein and mRNA expression of key enzymes like tyrosinase, tyrosinase-related protein-1 (TRP-1), and tyrosinase-related protein-2 (TRP-2). This action is further supported by the downregulation of myophthalmosis-related transcription factor expression and inhibition of cAMP-related binding protein phosphorylation. Additionally, the extract demonstrates potential photoprotective activity by enhancing keratinocyte viability and mitigating intracellular reactive oxygen species (ROS) production and apoptosis triggered by UVA and UVB irradiation. Lignans and triterpenoids are considered primary bioactive constituents contributing to its antioxidant and anti-inflammatory activities.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

While anthocyanins from the related Kadsura coccinea species demonstrated stability below pH 4, specific stability parameters for the combined KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT are not currently defined.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No direct safety assessments or maximum concentration guidelines have been established by regulatory bodies such as CIR, SCCS, or FDA specifically for KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While mechanistic data from related species suggests promising multi-functional benefits, the lack of direct clinical studies for KADSURA JAPONICA BRANCH/FRUIT/LEAF EXTRACT necessitates further research to confirm its precise efficacy and safety for skin.

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