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Moumoujus

KADSURA COCCINEA ROOT EXTRACT.

Insufficient Data / ANTIOXIDANT, SKIN CONDITIONING

Kadsura Coccinea Root Extract is a multi-functional botanical ingredient recognized for its potent antioxidant, skin conditioning, and anti-melanogenic properties. It also offers anti-inflammatory and photoprotective benefits, contributing to overall skin health and luminosity.

Summary

Antioxidant Skin conditioning Brightening Anti-inflammatory Photoprotective

Science

Mechanism of Action

This extract operates as a significant antioxidant, actively preventing the oxidative deterioration of cosmetic formulations and skin cells. Its primary skin benefit lies in its anti-melanogenic capabilities, demonstrated by a notable reduction in intracellular melanin content and tyrosinase activity in α-MSH-stimulated melanocytes. This is achieved by downregulating the protein and mRNA expression of key enzymes: tyrosinase, tyrosinase-related protein-1 (TRP-1), and tyrosinase-related protein-2 (TRP-2). Specifically, Kadsuralignan F, a component within the extract, inhibits melanin synthesis via tyrosinase degradation. Furthermore, it exhibits anti-inflammatory effects by inhibiting nitric oxide (NO) production and offers photoprotective qualities, safeguarding the skin from environmental stressors.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The anthocyanin-rich extract of Kadsura coccinea exhibits pH sensitivity, with its color vividly altering from slightly red to yellow in response to pH changes in the range of 4–8. This indicates that certain active components may be unstable or change characteristics within this pH range. The fruit extract itself naturally possesses a pH value of 4.2–4.8.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

No specific safety assessments by major regulatory bodies like CIR, SCCS, or FDA were found for Kadsura Coccinea Root Extract. Its absence from FDA's Voluntary Cosmetics Reporting Program for reported uses suggests it has not undergone extensive formal review for cosmetic applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Despite exhibiting promising in-vitro mechanisms for skin brightening, antioxidant, and anti-inflammatory effects, Kadsura Coccinea Root Extract's current profile is limited by a lack of clinical efficacy studies and comprehensive safety assessments by regulatory bodies, rendering its widespread recommendation as 'insufficient-data'.

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