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Moumoujus

JUNIPERUS EXTRACT ACETYLATED.

Insufficient Data CAS 83984-78-5 / PERFUMING

Juniperus Extract Acetylated is a botanical derivative whose potential benefits in skincare are primarily inferred from extensive research on non-acetylated juniper extracts and essential oils. These related forms are recognized for their potent antioxidant, anti-inflammatory, and antimicrobial properties. They show promise in regulating sebum production, preventing comedone formation, and contributing to overall skin vitality through hydration and potential collagen support.

Summary

Fragrance Ingredient Antioxidant Anti-inflammatory Antimicrobial Sebum Regulator Humectant Collagen Booster

Science

Mechanism of Action

The mechanism of action, largely extrapolated from non-acetylated juniper forms, involves multifarious pathways. It functions as an antioxidant by mitigating oxidative and nitrosative stress. Anti-inflammatory effects are observed through the suppression of inflammatory signaling pathways, including reductions in NF-κB activity and IL-1β. Antimicrobially, it targets prevalent skin bacteria like P. acnes and S. epidermidis. Astringent qualities contribute to sebum control and inhibit comedone development. Furthermore, components such as polysaccharides may act as humectants, and flavonoid glycosides might stimulate collagen biosynthesis.

Research

Clinical Evidence

Low confidence
Effective range 0.125–0.25%
Optimal

N/A

Key findings

  1. 01 In vitro studies on non-acetylated Juniperus communis oil demonstrated significant antimicrobial activity against P. acnes (MIC 0.125%) and S. epidermidis (MIC 0.250%). These studies also indicated anti-comedogenic effects via reduction in sebum production and prevention of comedone formation.
  2. 02 An experimental model utilizing non-acetylated Juniperus communis L. Needle Extract revealed its capacity to attenuate oxidative and nitrosative stress while suppressing inflammatory signaling, characterized by decreased NF-κB activity and reduced IL-1β, in a concentration-dependent manner.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Juniper essential oils, from which this extract is derived, are known to be sensitive to UV radiation and heat. Optimal storage involves amber glass bottles, protected from direct heat and light, to preserve ingredient stability.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed data insufficient for supporting the safety of several non-acetylated Juniperus extracts in cosmetic formulations. Critically, no specific CIR safety assessment for 'JUNIPERUS EXTRACT ACETYLATED' has been published. While Juniperus communis berry oil is listed by the FDA, the unique acetylated form requires dedicated safety evaluation, which is currently lacking.

Your Skin

Skin Compatibility

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While non-acetylated juniper extracts demonstrate compelling potential for addressing acne, oiliness, and inflammation, the absence of specific clinical efficacy and safety data for JUNIPERUS EXTRACT ACETYLATED necessitates extensive further research for its confident integration into precision skincare.

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