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Moumoujus

JULIANA ADSTRINGENS BARK EXTRACT.

Insufficient Data CAS 92797-35-8 / SKIN CONDITIONING

Derived from the bark of Juliana Adstringens, this extract is recognized for its comprehensive skin conditioning capabilities. It is traditionally valued for its antiseptic and anti-inflammatory properties, making it relevant for improving overall skin health and assisting in wound recovery.

Summary

Skin conditioning Anti-inflammatory Wound healing support Antimicrobial Antiseptic Hair growth stimulant Anti-dandruff agent Melasma reduction

Science

Mechanism of Action

JULIANA ADSTRINGENS BARK EXTRACT functions by maintaining the skin's healthy condition. Its primary actions include inhibiting pro-inflammatory mediators and reducing nitric oxide production, contributing to anti-inflammatory effects. Key metabolites, such as 3α-hydroxymasticadienoic acid and anacardic acids, stimulate angiogenesis to support wound healing. Anacardic acids also confer modest antimicrobial benefits, traditionally supporting its use for various skin concerns including wounds and melasma.

Research

Clinical Evidence

Medium confidence
Effective range 0.0001–25%
Optimal

N/A

Key findings

  1. 01 A ground stem bark extract concentration between 2.5% and 25% was observed to stimulate hair growth in both human and animal subjects.
  2. 02 An ethanol extract of the stem bark, used in cosmetic formulations at concentrations ranging from 0.0001% to 20%, demonstrated effectiveness in mitigating hair loss and counteracting dandruff.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability has been identified. The extract demonstrates versatility in formulation, as it can be obtained using a variety of solvents including water, ethanol, hexane, and petroleum ether, suggesting its components possess broad solubility across aqueous and oil-based systems.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Formal safety assessments by organizations such as CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) are not documented for JULIANA ADSTRINGENS BARK EXTRACT. Animal studies involving a synonym, Amphipterygium adstringens, indicated no acute toxicity or lethal effects at high oral doses (1200-2000 mg/kg body weight) in mice, with powdered bark extracts showing LD50 values above 5g. However, comprehensive topical safety and sensitization data are still pending, as noted by its unrated status from independent reviewers like Paula's Choice.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While JULIANA ADSTRINGENS BARK EXTRACT presents a promising array of benefits including skin conditioning, anti-inflammatory, and hair-stimulating properties supported by patent data, the current absence of formal safety reviews and definitive skin compatibility metrics indicates insufficient data for a precise assessment.

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