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Moumoujus

JUGLANS REGIA SEED.

Valuable CAS 84012-43-1 / ABRASIVE

Juglans Regia Seed, also known as Walnut Seed, offers a multifaceted approach to skincare by acting as a potent antioxidant, shielding the skin from environmental stressors. Rich in beneficial fatty acids and phenolic compounds, it deeply moisturizes and nourishes, while also providing anti-inflammatory and texture-improving properties.

Summary

Antioxidant Anti-inflammatory Astringent Emollient Hair Conditioning Humectant Moisturizing Skin Conditioning Antimicrobial Texture Enhancer

Science

Mechanism of Action

This ingredient provides antioxidant protection by neutralizing free radicals and safeguarding against environmental damage, UV radiation, and signs of premature aging, primarily due to its content of vitamin E, flavonoids, and tannins. It contributes to skin health through anti-inflammatory actions, helping to alleviate redness and irritation. Furthermore, its unique composition, including linoleic acid, vitamin E, zinc, and magnesium, supports enhanced collagen and elastin production, leading to improved skin texture, diminished fine lines, and an even tone. Walnut extracts also exhibit mild astringent qualities, which can help minimize the appearance of pores and manage excess sebum, alongside documented antibacterial and antifungal effects for clearer skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies on *Juglans regia leaf extracts* have shown potent anti-proliferative activity against mice and human melanoma cell lines, with IC50 values reported between 0.234 mg/mL and 0.350 mg/mL.
  2. 02 Further in vitro research indicated that *J. regia leaf extract* maintained HaCaT cell viability up to 98% at a concentration of 400 µg/mL and achieved over 40% bacterial mortality against *Proteus vulgaris*-infected HaCaT cells at a non-toxic concentration of 200 µg/mL.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Optimal stability for walnut extracts is generally achieved at pH values close to neutral. The ingredient's solubility varies by form: Juglans Regia Seed Oil is oil-soluble, while Juglans Regia Seed Extract is water-soluble.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While generally considered favorable, individuals with known nut sensitivities should exercise caution and perform a patch test due to potential allergic reactions. Low potential for irritation to skin, eyes, or lungs has been specifically noted for Juglans Regia (Persian Walnut) Shell Extract, suggesting a generally mild profile for related forms.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Juglans Regia Seed offers a versatile profile for skin health, providing antioxidant and moisturizing benefits with a low risk of irritation, making it a valuable addition to many skincare formulations, though direct clinical efficacy data for seed extract in topical applications is limited.

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