Science
Mechanism of Action
This ingredient operates by significantly reducing the interfacial tension between immiscible phases, such as oil and water, thereby enabling the formation and stability of emulsions. Its surfactant properties also facilitate cleansing and aid in foam production. Due to its 22 ethoxylate units, ISOSTEARETH-22 exhibits strong hydrophilic characteristics, making it an effective oil-in-water (O/W) emulsifier and solubilizer for hydrophobic components within aqueous systems.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
ISOSTEARETH-22 functions as a fundamental excipient, not an active ingredient typically 'dusted' at low, potentially ineffective concentrations. Its primary role is structural and functional within the formulation itself.
The Formula
Formulation
Stability
No specific optimal pH range for ISOSTEARETH-22 itself has been identified. However, general skincare formulations, where this ingredient is used, typically maintain pH levels between 4.5 and 6.5 for optimal stability and performance. The number of ethoxylate units, in this case 22, directly correlates with increased hydrophilicity and water solubility for PEG derivatives of fatty alcohols.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that alkyl PEG ethers, including Isosteareth-22, are safe under current practices of use and concentration, provided they are formulated to be non-irritating. This safety assessment covers a maximum concentration of 1% in leave-on products and 2% in rinse-off formulations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
ISOSTEARETH-22 is a valuable formulation excipient, effectively stabilizing oil-in-water emulsions and solubilizing hydrophobic ingredients, with a strong safety profile at recommended concentrations for diverse cosmetic applications.
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