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Moumoujus

ISOSTEARAMIDE MIPA.

Valuable CAS 55738-53-9 / ANTISTATIC, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, VISCOSITY CONTROLLING

Isostearamide MIPA is a multifunctional cosmetic ingredient primarily serving as a surfactant, emulsifier, and conditioning agent. It efficiently blends oil and water, enhances product stability, and improves the performance and sensory qualities of various cleansing and conditioning formulations.

Summary

Antistatic Foam boosting Surfactant Viscosity controlling Cleansing Conditioning agent Emulsifier

Science

Mechanism of Action

This ingredient functions by reducing the surface tension between liquids, allowing for the stable mixing of immiscible phases like oil and water within emulsions. As a surfactant, it boosts foam generation and cleansing efficacy, while also noted to mitigate the irritating potential of other surfactants in a blend. Beyond cleansing, it acts as a conditioning and antistatic agent, improving the texture, consistency, and overall feel of cosmetic products on the skin and hair.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Undiluted application (0.5 mL) resulted in erythema with scores of 1.7 – 2 out of a maximum of 4, persisting until day 5 and fully resolving by day 8. This indicated Isostearamide MIPA was not considered irritating to rabbit skin.
  2. 02 Undiluted application (0.1 mL) produced slight conjunctival reactions, specifically chemosis (≤ 1) and enanthema (1-2) at 1 hour. These effects were completely reversible, with no observed irritation at 24, 48, or 72 hours, leading to the conclusion that it was not irritating to the rabbit eye.

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding 'dusting' or transparency concerns for Isostearamide MIPA were identified in the available research.

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Isostearamide MIPA maintains its integrity and function across diverse formulation environments. It is frequently co-formulated with other surfactants, a practice that enhances overall cleansing properties and optimizes skin tolerance.

Synergies

  • Other surfactants (for improved cleansing efficiency, foam characteristics, and enhanced skin compatibility)

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk Low

The CIR Expert Panel has concluded that Isostearamide MIPA, along with other alkyl amide MIPA ingredients, is safe for cosmetic use under current practices of use and concentration, provided products are formulated to be non-irritating. While undiluted tests on rabbit skin and eyes showed minimal irritation, the Panel highlighted the potential for dermal or ocular irritation if formulations are not properly adjusted. Maximum concentration guidelines for similar MIPA ingredients include up to 0.4% in leave-on dermal products (e.g., Oleamide MIPA) and up to 12% in rinse-off hair bleaches (e.g., Cocamide MIPA). In vitro studies indicated clastogenic activity in Chinese hamster lung fibroblasts, though in vivo studies (UDS assay, micronucleus test) showed no genotoxic effects.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Isostearamide MIPA is a valuable functional ingredient, integral for Moumoujus formulations requiring robust emulsification, controlled viscosity, enhanced cleansing, and conditioning, particularly given its low inherent irritation potential when properly incorporated.

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