Science
Mechanism of Action
This compound primarily functions by modifying the physical properties of formulations as a plasticizer, by dissolving other substances as a solvent, and by improving the feel or appearance of skin as a conditioning agent.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Reports indicate good stability across a range of pH conditions, as well as when exposed to light and heat, suggesting robust integration into various formulations.
Safety
Safety Profile
The ingredient, also known as '1H-Isoindole-1,3(2H)-dione, 2-(1-methylethyl)-', does not possess individual FDA approval but may be used as a component within products adhering to broader group standards. Aggregated GHS data indicates potential for harm if swallowed (H302) in 75.9% of reports and serious eye irritation (H319) in 72.2% of reports. Conversely, Environment Canada classifies it as not expected to be toxic or harmful, persistent, or bioaccumulative. EWG Skin Deep assigns 'LOW' concern ratings for cancer, allergies & immunotoxicity, and developmental and reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Isopropylphthalimide offers functional benefits as a plasticizer, solvent, and skin conditioner; however, its 'not reviewed' CIR status and consistent reporting of serious eye irritation in aggregated GHS data raise significant questions regarding its suitability for precision skincare.
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References
Sources