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ISOMERIZED SAFFLOWER GLYCERIDES.

Valuable CAS 303101-61-3 / ORAL CARE, SKIN CONDITIONING

Isomerized Safflower Glycerides, a derivative of safflower oil, functions as an effective skin conditioning emollient. It significantly contributes to softening and smoothing the skin by reinforcing the epidermal barrier.

Skin Conditioning Emollient Barrier Support Humectant

Science

This ingredient acts as a powerful skin conditioning emollient, primarily due to its composition as a triglyceride of conjugated linoleic acid, derived from safflower oil. It delivers essential fatty acids, specifically linoleic acid, which are critical for strengthening the epidermal barrier and thus minimizing transepidermal water loss (TEWL). Additionally, its inherent phytosterols serve as humectants, attracting and retaining water within the skin to boost hydration. Its light texture and rapid absorption make it a versatile choice for a diverse range of skin types.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

While specific stability data for Isomerized Safflower Glycerides is not detailed, the general principles for safflower oil suggest storage in a cool, dark environment to prevent oxidation, which could alter its properties and potentially increase comedogenicity. It is insoluble in water but miscible with oil and fat solvents.


Safety

CIR Status
Safe with restrictions
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has evaluated Isomerized Safflower Glycerides within the broader category of triglycerides, concluding they are generally safe for cosmetic applications when formulated to mitigate potential irritation. While a specific maximum concentration for Isomerized Safflower Glycerides itself is not provided, a separate CIR review deemed related PEGylated alkyl glycerides safe up to 10% in leave-on products. Safflower oil, its foundational component, is recognized by the FDA as an approved indirect food additive and a common food ingredient. The EWG Skin Deep database indicates a low concern for irritation (skin, eyes, lungs) but notes the weight of evidence for this specific concern as unknown/unassessed.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Isomerized Safflower Glycerides is a valuable emollient and skin conditioner, effectively enhancing barrier function and hydration for a wide range of skin types, though specific clinical dose-response data is currently limited.


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