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ISOLEPTOSPERMONE.

Insufficient Data CAS 5009-05-2 / HAIR CONDITIONING, SKIN CONDITIONING

Isoleptospermone is a β-triketone naturally derived from *Leptospermum* plant species, including Manuka. It is recognized for its antimicrobial properties and is inferred to support skin health through anti-inflammatory, antioxidant, and barrier-repairing effects.

Antimicrobial Anti-inflammatory Antioxidant Skin Barrier Support Skin Conditioning Wound Healing

Science

As a β-triketone, Isoleptospermone exhibits known antimicrobial activity. Its presence as a component in plant essential oils suggests an inferred role in modulating inflammatory responses, neutralizing free radicals, promoting the skin's natural healing processes, and fortifying the skin barrier function.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient is susceptible to degradation by light, air, and elevated temperatures. For optimal stability, it should be stored in dry, dark conditions, preferably at 0-4°C for short-term preservation (days to weeks) and -20°C for long-term storage (months to years).


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

While registered in the FDA Global Substance Registration System (GSRS) as a cosmetic ingredient, Isoleptospermone currently lacks specific safety assessments from either the Cosmetic Ingredient Review (CIR) expert panel or the Scientific Committee on Consumer Safety (SCCS).


Your Skin

No Normal
No Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Insufficient Data

While showing promising inferred biological activities, the lack of specific safety assessments and direct clinical efficacy data for Isoleptospermone necessitates further research for a definitive Moumoujus recommendation.


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