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Moumoujus

ISOHEXYL NEOPENTANOATE.

Valuable CAS 131141-70-3 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Isohexyl Neopentanoate is a synthetic alkyl ester that functions primarily as a skin conditioning agent and emollient. It enhances the skin's natural barrier and significantly improves hydration by reducing transepidermal water loss.

Summary

Skin conditioning Emollient Skin barrier support Hydration enhancement Sensory improvement (texture, spreadability) Solvent (for UV filters, pigments)

Science

Mechanism of Action

This ingredient operates by depositing exogenous lipids onto the skin's surface, effectively filling microscopic gaps within the stratum corneum's intercorneocyte clusters. This action fortifies the skin barrier, leading to enhanced hydration and protection against transepidermal water loss (TEWL). Furthermore, it significantly improves the tactile experience of cosmetic formulations, imparting a smooth, non-greasy, and silky feel, while also boosting product spreadability.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that alkyl esters, including Isohexyl Neopentanoate, are safe for use in cosmetic applications when formulated to be non-irritating. There is a low reported risk of causing skin irritations or allergic reactions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Isohexyl Neopentanoate is a valuable emollient and skin conditioning agent, enhancing barrier function and providing a superior sensory experience with a favorable safety profile across all skin types.

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