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ISOHEXADECANE.

Valuable CAS 4390-04-9, 60908-77-2, 93685-80-4 / SKIN CONDITIONING - EMOLLIENT, SOLVENT

Isohexadecane is a lightweight, non-greasy synthetic hydrocarbon that functions as a highly effective emollient, solvent, and texture enhancer in precision skincare formulations. It imparts a smooth, silky feel, enhancing spreadability and forming a subtle, breathable protective barrier on the skin's surface.

emollient solvent skin conditioning texture enhancer barrier support

Science

On the skin, Isohexadecane acts as a non-occlusive emollient, delivering a smooth and soft sensation while minimizing transepidermal water loss by forming a delicate protective film. Its large molecular structure prevents significant skin penetration, ensuring surface-level benefits without hindering natural skin functions. As a solvent, it facilitates the even dissolution and distribution of other active ingredients and pigments. Furthermore, it significantly improves product aesthetics by enhancing spreadability and slip, contributing to a desirable dry-touch finish.


Research

Low confidence
Effective range 2–50%
Optimal

N/A


Transparency

Not commonly dusted

Data regarding specific 'dusting' properties or thresholds for Isohexadecane is not available in the provided research. It is primarily valued for its liquid emollient and solvent characteristics.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Isohexadecane exhibits high stability across a wide pH spectrum, from acidic to slightly alkaline conditions. It is resistant to oxidation and degradation during various processing steps, including heating, cooling, and emulsification, and remains inert when combined with other ingredients.


Safety

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has determined Isohexadecane to be safe for use in cosmetic applications. While highly concentrated forms may carry irritation warnings, its inclusion in cosmetic formulations rarely triggers allergic reactions or skin irritation. The FDA also acknowledges similar synthetic isoparaffin hydrocarbons in certain food-related applications.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Isohexadecane is a valuable inert emollient and solvent that significantly improves product texture and spreadability while offering universal skin compatibility and an excellent safety profile.


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