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Ingredient directory

Isodon Serra Leaf/stem Extract

Derived from the Isodon serra plant, this extract is recognized for its diverse bioactive compounds, particularly ent-kaurane diterpenoids. It offers multifaceted benefits, including antioxidant and anti-inflammatory properties, with potential for addressing hyperpigmentation and signs of aging.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

antioxidant anti-inflammatory skin brightening (potential) anti-aging (potential) sebum regulation (potential)

Science

ISODON SERRA LEAF/STEM EXTRACT functions primarily through its ent-kaurane diterpenoid content. These compounds contribute to its antioxidant capabilities by neutralizing free radicals and its anti-inflammatory action, specifically through the demonstrated inhibition of nitric oxide (NO) production. Research also suggests a potential for inhibiting melanogenesis, thereby contributing to skin brightening, and exhibiting anti-aging effects by influencing cellular processes.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Formulators should be aware that this extract may present aesthetic or stability challenges that could limit its practical application in certain formulations.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

A formal safety assessment by regulatory bodies such as CIR, SCCS, or FDA is not available for ISODON SERRA LEAF/STEM EXTRACT. While often considered non-irritating, there is a noted likelihood of skin irritation, inflammation, or dryness, especially when combined with other potentially problematic ingredients.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

While offering promising antioxidant, anti-inflammatory, and potential brightening/anti-aging benefits, the lack of formal safety assessments, specific clinical efficacy data, and noted formulation challenges necessitate caution.


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