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ISOCETYL PALMITATE.

Valuable CAS 127770-27-8 / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Isocetyl Palmitate is a skin conditioning emollient that enhances the feel and appearance of the skin by forming a protective barrier. This water-insoluble ester effectively reduces moisture loss, leading to improved hydration and a smoother, more supple skin texture. It also shows promise in optimizing the penetration of other active ingredients into the skin.

Emollient Skin Conditioning Occlusive Moisture Retention Permeation Enhancer

Science

Functioning primarily as an emollient, Isocetyl Palmitate smooths and softens the skin surface. Its occlusive properties stem from its water-insolubility, enabling it to create a hydrophobic film that minimizes transepidermal water loss and sustains skin moisture. Additionally, this ingredient can interact with lipid bilayers within biological membranes, influencing their fluidity and permeability, which may facilitate the enhanced absorption of active ingredients in topical formulations.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Isocetyl Palmitate demonstrates chemical stability under standard ambient conditions, contributing to the overall consistency and longevity of cosmetic formulations. For optimal preservation, it is recommended to store the ingredient tightly closed and in a dry environment.


Safety

CIR Status
Safe with restrictions
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has deemed Isocetyl Palmitate safe for use in cosmetics, contingent upon specific concentration or usage limitations. However, the CIR also indicated that data regarding skin, eye, or lung irritation is 'unknown/unassessed.' No specific SCCS or FDA regulatory status was identified.


Your Skin

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Isocetyl Palmitate is a valuable emollient and occlusive ingredient, enhancing skin hydration and texture while potentially improving the delivery of other active compounds in formulations.


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