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ISOBUTYL PROPIONATE.

Questionable CAS 540-42-1 / PERFUMING

Isobutyl Propionate is an ester primarily utilized as a solvent, chemical intermediate, and fragrance component. While present in some food flavorings, it lacks established direct skincare benefits.

Fragrance Solvent

Science

As an ester, Isobutyl Propionate may exert general biological effects or influence cell membrane integrity. However, its specific mechanism of action to provide direct benefits for skin health has not been identified or studied.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

This ingredient is not commonly 'dusted' or misused for efficacy, as its primary roles are as a solvent or fragrance agent, not a direct active for skin benefits.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Isobutyl Propionate is an ester susceptible to hydrolysis in the presence of water, which can revert it to its parent alcohol and acid. It is a flammable liquid and vapor, necessitating avoidance of heat, sparks, open flames, direct sunlight, and extreme temperatures during storage and handling.

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Strong bases

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Data indicates Isobutyl Propionate is classified with R38, signaling it is irritating to skin. Prolonged skin contact may induce temporary irritation, and inhalation or direct contact can irritate or burn skin and eyes. While deemed safe at current levels of intake as a flavoring agent by JECFA and listed by the FDA for this use, its direct application to skin warrants caution due to irritation potential.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Questionable

Given its classification as irritating to skin and the absence of established direct skincare benefits, Isobutyl Propionate is a questionable ingredient for precision skincare formulations.


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