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ISOBUTYL ISOBUTYRATE.

Questionable CAS 97-85-8 / PERFUMING

Isobutyl isobutyrate primarily functions as a skin-conditioning agent, imparting a smooth feel and improving product texture. It also serves as a solvent and a perfuming ingredient in formulations. While studies indicate low acute toxicity, it is noted as a slight skin irritant and rapidly metabolizes upon skin contact.

Skin-conditioning Solvent Perfuming

Science

On the skin, isobutyl isobutyrate primarily acts as a conditioning agent, contributing to a smooth skin feel and optimizing product spreadability. It also functions as a solvent within formulations. Upon absorption, it undergoes rapid hydrolysis, breaking down into isobutanol and isobutyric acid.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

It exhibits general stability under typical conditions. However, it reacts exothermically with acids, generating heat and forming alcohols and acids. Similar heat generation occurs upon interaction with caustic solutions.

Conflicts

  • acids
  • caustic solutions
  • strong oxidizing acids
  • alkali metals
  • hydrides

Safety

CIR Status
Not reviewed
Sensitization risk Low

Isobutyl isobutyrate is classified as a slight skin irritant. In vivo, it rapidly undergoes hydrolysis into isobutanol and isobutyric acid. Studies indicate low acute toxicity in experimental animals. It is also approved for use as a food flavorant under the Federal Food, Drug and Cosmetic Act.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Questionable

While offering textural benefits and a smooth skin feel, its classification as a slight skin irritant and unreviewed CIR safety status suggest caution for precision skincare applications.


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