Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

ISOAMYL ACETATE.

Valuable CAS 123-92-2 / SOLVENT

Isoamyl Acetate is a versatile ester primarily valued for its distinct banana or pear-like aroma, functioning as a key fragrance component. Beyond its olfactory contribution, it acts as an effective solvent, aiding in the dispersion of other ingredients within cosmetic formulations.

Summary

Fragrance Ingredient Solvent

Science

Mechanism of Action

This ingredient functions primarily as a solvent, enabling the dissolution and uniform distribution of other compounds within a product matrix. Additionally, it serves as a fragrance agent, imparting a characteristic fruity aroma to formulations.

Research

Clinical Evidence

High confidence
Effective range 0.003–0.22%
Optimal

N/A

Key findings

  1. 01 No irritation was observed in an 8-hour closed patch test at an 8% concentration in 25 human subjects, with no sensitization reactions noted in a maximization test.
  2. 02 Typical concentrations for use range from 0.003% in creams and lotions to 0.05% in soaps and perfumes.
  3. 03 The highest reported use concentration in a cosmetic formulation is 0.22% (2022 FDA VCRP data).

Transparency

Dusting Analysis

Not commonly dusted

Isoamyl Acetate functions as a liquid solvent and fragrance, therefore it is not associated with 'dusting' in formulations.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

As an ester, Isoamyl Acetate is prone to hydrolysis when exposed to moisture, strong acids, or strong bases, which can compromise its olfactory properties. Formulations should ideally maintain a neutral pH and minimize water exposure. It exhibits good oxidative stability under standard storage conditions but has a low flashpoint of approximately 25°C, necessitating careful handling and storage away from ignition sources.

Conflicts

  • strong oxidizing agents
  • strong acids
  • alkaline materials
  • nitrates

Safety

Safety Profile

CIR Status
Safe as used
Max tested
0.22%
Pregnancy
Safe
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded Isoamyl Acetate is safe for use in cosmetic products, a finding reaffirmed in 2022 considering its use up to 0.22%. It is approved for use in Europe and holds Generally Recognized As Safe (GRAS) status by FEMA as a flavoring agent. The FDA also approves its use as an indirect food additive, and the EPA found no toxicological concerns for its use as an inert ingredient, including for infants and children.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Isoamyl Acetate is a valuable ingredient, safely employed within its established concentration ranges (up to 0.22%) as both a fragrance and solvent in a variety of cosmetic formulations, demonstrating low risk for irritation or sensitization.

Related

Similar Ingredients

Finding similar ingredients…