Science
Mechanism of Action
The extract functions as a robust antioxidant by effectively scavenging free radicals, thereby protecting skin cells from oxidative stress. It actively inhibits collagenase, an enzyme responsible for collagen breakdown, while simultaneously stimulating human fibroblast proliferation and enhancing cellular collagen production. This dual action supports skin repair and renewal, contributing to anti-aging effects. Furthermore, it modulates inflammatory responses through the inhibition of prostaglandin synthesis and interference with leukocyte migration, alongside demonstrating notable antimicrobial and antibacterial capabilities.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 At a concentration of 0.031 mg/mL, the extract significantly enhanced human fibroblast proliferation and reduced wound area by 9.76% (with IPC70) and 15.68% (with IPC95) in vitro, demonstrating wound healing and anti-aging potential.
- 02 In vitro testing at 62.3 µg/mL inhibited prostaglandin synthesis, indicating notable anti-inflammatory effects.
- 03 An in vitro study demonstrated significant antioxidant activity, with 56.12% scavenging effect on DPPH radicals at 1000 mg/mL.
- 04 The extract exhibited in vitro antibacterial activity against various Gram-positive and Gram-negative bacteria at concentrations between 75-100 µg/ml.
Transparency
Dusting Analysis
Information regarding 'dusting' practices or specific low-efficacy thresholds for this ingredient is not available in the provided research data.
The Formula
Formulation
Safety
Safety Profile
In vitro studies suggest effectiveness at concentrations that are noncytotoxic. Comprehensive safety reviews by regulatory bodies such as CIR are not yet available for this ingredient.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With proven antioxidant, anti-inflammatory, and regenerative properties, Ipomoea pes-caprae flower/leaf/stem extract is a valuable multi-functional ingredient for diverse skin health applications, suitable for all skin types with low irritancy.
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References
Sources