Science
Mechanism of Action
This extract operates through multiple pathways to enhance skin vitality. Its rich composition, including saponins and alkaloids, confers significant antioxidant activity, effectively neutralizing free radicals that instigate oxidative stress and premature aging. Concurrently, it exhibits antimicrobial effects against common skin bacteria. Furthermore, it supports skin elasticity, aiming to diminish the appearance of fine lines and wrinkles, and is historically valued for addressing concerns like dry skin and hyperpigmentation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An in vitro study demonstrated that a methanol extract possessed antibacterial activity against Escherichia coli and Pseudomonas aeruginosa.
- 02 An ethyl acetate soluble fraction exhibited 83.26% inhibition of DPPH free radical scavenging activity, with an IC50 of 60.28 µg/mL, signifying robust antioxidant capabilities.
Transparency
Dusting Analysis
Insufficient data available to determine common dusting practices or thresholds for this ingredient.
The Formula
Formulation
Safety
Safety Profile
While the Cosmetic Ingredient Review (CIR) has not formally assessed this ingredient, oral toxicity studies in mice indicated an LD50 value of 229.2 mg/kg for a crude methanol extract. Adverse effects, including convulsions, tremors, and respiratory distress leading to death, were observed starting at 300 mg/kg, highlighting dose-dependent toxicity via oral ingestion. It is categorized as a cosmetic ingredient for skin protection and is not recommended for fragrance or flavor applications.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ipomoea Hederacea Seed Extract presents as a valuable ingredient with demonstrated antioxidant and antimicrobial efficacy, offering promising benefits for overall skin health and protection.
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References
Sources