Science
Mechanism of Action
This extract is a rich source of essential nutrients, vitamins (A, C, E), minerals, beta-carotene, and antioxidant polyphenols. Its action on the skin encompasses powerful antioxidant protection, effectively neutralizing free radicals to minimize the appearance of maturing skin. It is highly effective at moisturizing and hydrating, locking in moisture to leave the skin soft, smooth, and supple. With inherent soothing properties, it can calm irritated or sensitive skin, visibly reducing redness and irritation. The extract's vitamin C content aids in brightening the complexion, reducing the appearance of dark spots and hyperpigmentation for a more even skin tone. Additionally, it strengthens the skin's natural barrier against environmental stressors and exhibits immunomodulatory, anti-inflammatory effects through concentration-dependent inhibition of pro-inflammatory cytokines such as Interleukin-6 (IL-6), Tumor Necrosis Factor alpha (TNF-alpha), Monocyte Chemoattractant Protein-1 (MCP-1), and Prostaglandin-E2 (PGE-2).
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies using murine macrophages demonstrated concentration-dependent anti-inflammatory effects: at 75 µg/mL, a 31% inhibition of the pro-inflammatory cytokine Interleukin-6 (IL-6) was observed.
- 02 Increasing the extract concentration to 100 µg/mL in murine macrophages resulted in a notable 73% inhibition of IL-6 production.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Key components like anthocyanins are stable and exhibit a red color in acidic conditions (pH 1-3), with observed absorption peaks at pH 1 and pH 4.5. However, polyphenols present in the extract are often susceptible to degradation from environmental factors such as air and pH, suggesting that protective measures like encapsulation could enhance stability in formulations.
Safety
Safety Profile
Specific safety evaluations by CIR, SCCS, or FDA for IPOMOEA BATATAS ROOT LEES EXTRACT are currently unavailable. General 'Ipomoea Batatas Root Extract' is noted by EWG to have low concerns regarding cancer, allergies, immunotoxicity, and developmental or reproductive toxicity, and is listed as 'Irritant Free' by SkinSAFE. Studies on Ipomoea batatas extracts demonstrate non-toxic effects up to 4000 mg/kg in rats and 1000 µg/ml in vitro on rabbit articular chondrocytes. It is important to distinguish that an ethanolic extract derived from *Ipomoea batatas leaves* (a different part of the plant) at 1000 ppm and 5000 ppm did cause irritation in 2 out of 7 subjects in a patch test, a finding not directly applicable to the root lees extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ipomoea Batatas Root Lees Extract is a valuable, multifunctional ingredient offering significant antioxidant, hydrating, and anti-inflammatory benefits, making it highly suitable for all skin types.
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