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Moumoujus

IPOMOEA BATATAS LEAF EXTRACT.

Valuable CAS - / SKIN CONDITIONING - EMOLLIENT

Ipomoea Batatas Leaf Extract offers a precision approach to skin health, leveraging a rich spectrum of antioxidants to neutralize free radicals and diminish oxidative stress. This botanical ingredient simultaneously soothes, hydrates, and brightens the complexion, while exhibiting beneficial antimicrobial and immunomodulatory properties for enhanced skin resilience.

Summary

Antioxidant Anti-inflammatory Antimicrobial Moisturizing Skin Conditioning Skin Brightening Barrier Strengthening Soothing

Science

Mechanism of Action

Ipomoea Batatas Leaf Extract functions through its diverse composition of bioactive compounds, prominently polyphenols (including cynarin, neochlorogenic acid, and rutin), flavonoids, and vitamins A, C, and E. These potent antioxidants collaboratively neutralize free radicals, thereby reducing oxidative stress and offering protection against environmental damage. The extract also demonstrates anti-inflammatory effects by suppressing inflammatory mediators and inhibiting IL-6 production in inflammatory murine macrophages in a concentration-dependent manner. Interestingly, it can increase IL-6 production in unchallenged keratinocytes, indicating a nuanced immunomodulatory capacity. Furthermore, it enhances skin hydration, contributing to a softer and smoother skin texture by improving moisture retention. Its vitamin C content supports skin brightening by minimizing the appearance of dark spots and hyperpigmentation. The extract additionally strengthens the skin's natural barrier and exhibits antimicrobial activity against various bacterial strains, including antibiofilm properties.

Research

Clinical Evidence

High confidence
Effective range 0.002676–0.5%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

Polyphenols, integral to the extract's efficacy, are sensitive to environmental factors like air and pH, exhibiting optimal antioxidant activity retention within a pH range of 5.0 to 7.0. Nano-capsulation is a potential strategy to enhance metabolite stability and dermal penetration.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Ipomoea Batatas Leaf Extract has not undergone formal safety review by CIR, SCCS, or FDA. A human patch test indicated a moderate risk of irritation, with 2 out of 7 subjects exhibiting a reaction to 'old' leaf extract at 0.1% (1000 ppm) and 0.5% (5000 ppm), whereas 'young' leaf extract showed reduced risk. In vivo acute toxicity studies in rats using Ipomoea batatas root and tuber extracts demonstrated a non-toxic profile up to 4000 mg/kg. EWG Skin Deep generally lists 'Ipomoea Batatas Root Extract' with low safety concerns.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Ipomoea Batatas Leaf Extract is a valuable ingredient, offering broad-spectrum benefits from antioxidant protection to immunomodulatory effects and hydration, though precise formulation is essential due to its stability profile and moderate potential for irritation at specific concentrations or extract types.

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