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Moumoujus

INGA EDULIS LEAF EXTRACT.

Valuable / ANTIOXIDANT

Inga Edulis Leaf Extract is a potent botanical, rich in polyphenols, offering a spectrum of benefits from enhancing the skin's natural defense mechanisms to addressing concerns like photoaging, inflammation, and hyperpigmentation. Its multi-targeted action makes it a versatile ingredient for precision skincare formulations.

Summary

Antioxidant Anti-inflammatory Photoprotective Anti-aging Skin Brightening Sebum Control Collagen Protection

Science

Mechanism of Action

This extract functions by increasing the skin's endogenous antioxidant potential, primarily due to its high polyphenol content. It provides photoprotective benefits by shielding against both UVA and UVB radiation. The extract exerts anti-inflammatory effects by significantly reducing pro-inflammatory markers such as MPO activity, IL-1β, TNF-α, and CXCL1/KC cytokines following UV exposure. Furthermore, it inhibits tyrosinase activity to mitigate hyperpigmentation, suppresses lipoxygenase activity to control sebum production, and inhibits MMP-1 activity to combat fine lines, wrinkles, and sagging, thereby reducing overall oxidative damage.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

1% (purified fraction)

Key findings

  1. 01 A topical formulation containing 1% of a purified Inga edulis fraction demonstrated an increase in the skin's endogenous antioxidant potential. Its key compounds, vicenin-2 and myricetin, effectively penetrated both the epidermis and dermis. In vitro, this fraction exhibited photoprotective efficacy against UVA and UVB radiation at concentrations of 25 and 50 mg/mL. In vivo studies confirmed its anti-inflammatory properties post-UVB exposure, evidenced by reduced MPO activity, IL-1β, TNF-α cytokines, and CXCL1/KC chemokine concentrations.

Transparency

Dusting Analysis

Not commonly dusted

There is no available data to suggest that Inga Edulis Leaf Extract is commonly 'dusted' at sub-efficacious percentages. The clinical data points to a specific effective concentration for its purified fraction.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Inga Edulis Leaf Extract and its purified fraction have demonstrated robust UV photostability, maintaining efficacy under light exposure.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by major regulatory bodies (CIR, SCCS, FDA) are not yet available. However, in vitro studies have indicated low cytotoxicity in fibroblast cells, suggesting a favorable safety profile for topical application without significant cellular harm.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Inga Edulis Leaf Extract is a valuable botanical offering comprehensive skin benefits, including potent antioxidant defense, photoprotection, anti-inflammatory action, and targeted improvements for aging, pigmentation, and oily skin concerns.

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