Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

INDIGOFERA TINCTORIA LEAF.

Valuable CAS 84775-63-3 / HAIR DYEING

Derived from the Indigofera tinctoria plant, this extract is a versatile botanical offering significant anti-inflammatory and antioxidant benefits. It actively supports the skin's barrier function, provides deep hydration, and helps mitigate visible signs of aging and irritation, making it suitable for a broad range of skin concerns.

Summary

skin conditioning anti-inflammatory agent antioxidant skin barrier support hydrating agent wound healing agent anti-aging agent redness reduction agent hyperpigmentation reducer

Science

Mechanism of Action

Indigofera tinctoria leaf extract operates through several key pathways: it reinforces the skin barrier and delivers profound hydration. Its anti-inflammatory properties soothe irritated and sensitive skin, effectively diminishing redness and discomfort. As a potent antioxidant, it neutralizes harmful free radicals, thereby reducing the visible markers of aging. The extract also accelerates wound healing by decreasing dermal inflammation and boosting antioxidant enzyme activity. Furthermore, its bioflavonoids exhibit an antihistamine-like action on the skin, reducing reactivity and targeting pathways associated with chronic redness, alongside helping to alleviate post-inflammatory hyperpigmentation (PIH).

Research

Clinical Evidence

Medium confidence
Effective range 2–5%
Optimal

N/A

Key findings

  1. 01 In rat models, topical application significantly accelerated wound healing, demonstrating a marked reduction in dermal inflammation and enhanced antioxidant enzyme activities within the skin.
  2. 02 This concentration range is recommended for optimal skincare formulation results, providing comprehensive benefits including skin barrier strengthening, deep hydration, and strong anti-inflammatory, antioxidant, and anti-aging properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 8 – 14
0 7 14

Stability

The extract exhibits low stability when exposed to light and high temperatures, with its colorant degrading at 40°C. To preserve color integrity, the pH of formulations should be maintained within the alkaline range of 8 to 14. Components like indigo and indirubin demonstrate solubility in chloroform and methanol, respectively. Refined extracts, unlike raw powder, are typically stain-free in creams and serums, and can be incorporated into both aqueous and oil phases.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
25%
Sensitization risk Moderate

The SCCS considers Indigofera tinctoria safe for non-oxidative hair coloring up to 25% on-head concentrations, though a weak skin sensitization potential cannot be entirely excluded. Individuals, especially those with sensitive skin, may experience allergies or irritation; a patch test is highly recommended. While EWG Skin Deep rates it 'LOW' for 'Allergies & Immunotoxicity' and 'Not likely to be mutagenic in humans', it notes that some in vitro extracts have demonstrated mutagenic effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Indigofera Tinctoria Leaf is a valuable botanical ingredient offering robust anti-inflammatory, antioxidant, and barrier-strengthening benefits across all skin types, with optimal efficacy observed between 2-5%.

Related

Similar Ingredients

Finding similar ingredients…