Science
Mechanism of Action
Impatiens Balsamina Extract operates through several pathways to enhance skin health. It demonstrates anti-inflammatory action by inhibiting the lipoxygenase pathway, reducing redness and irritation. Its antioxidant properties combat oxidative stress, while its ability to suppress elastase activity supports collagen integrity, contributing to anti-aging effects. Additionally, it aids in skin brightening by inhibiting tyrosinase activity and provides moisturizing and astringent benefits, helping to maintain skin hydration and refine appearance.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A 35% ethanolic extract significantly reduced pruritic effects in mouse models of dermatitis.
- 02 A 70% ethanol flower extract demonstrated strong inhibitory action on elastase activity, suggesting anti-aging potential.
- 03 A 95% ethanol flower extract showed superior tyrosinase inhibition compared to arbutin at the same concentration, indicating strong skin-whitening capabilities.
- 04 An unspecified concentration of leaf extract was effective in treating poison ivy rash in 108 out of 115 patients within 2-3 days.
- 05 A pink-colored extract at 163.5 ± 6.8 µg/mL exhibited anti-inflammatory potential in mouse macrophage cell lines.
Transparency
Dusting Analysis
No data available to suggest this ingredient is commonly dusted or has a specific dusting threshold.
The Formula
Formulation
Stability
Typically supplied as a clear to hazy colorless liquid, the extract maintains stability within a pH range of 5-7. While the plant can tolerate a broad soil pH, this does not reflect ingredient stability.
Safety
Safety Profile
Acute oral toxicity studies in rats showed no mortality or clinical signs of toxicity up to 5000 mg/KgBw for an n-hexane fraction of the leaf methanol extract, indicating a low systemic toxicity at this dose. However, a 35% hydroalcoholic stem extract was reported to be more toxic in C. elegans, affecting reproduction and lifespan due to compounds like lawsone. No specific CIR, SCCS, or FDA review status has been found.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Impatiens Balsamina Flower/Leaf/Stem Extract is a valuable botanical ingredient offering a broad spectrum of benefits including anti-inflammatory, anti-aging, and skin-brightening effects, with a generally low irritancy profile suitable for most skin types.
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References
Sources