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Moumoujus

IMMORTALIZED HUMAN TOOTH PULP STEM CELL CONDITIONED MEDIA.

Insufficient Data / ANTIPLAQUE, HAIR CONDITIONING, HUMECTANT, ORAL CARE

This ingredient comprises the bioactive secretome harvested from cultured immortalized human dental pulp stem cells. It delivers a sophisticated blend of growth factors, cytokines, and exosomes, anticipated to promote skin vitality, regeneration, and an enhanced dermal appearance.

Summary

Skin rejuvenation Promotes cell proliferation Enhances cell migration Supports anti-apoptosis Aids angiogenesis Increases oxidative stress resistance Facilitates tissue regeneration Supports wound healing Neuroprotection Skin brightening Improves skin clarity Enhances skin radiance

Science

Mechanism of Action

Immortalized human tooth pulp stem cell conditioned media exerts its influence via a complex array of signaling molecules. Predominant among these are growth factors such as Nerve Growth Factor (NGF), Vascular Endothelial Growth Factor (VEGF), Hepatocyte Growth Factor (HGF), and basic Fibroblast Growth Factor (bFGF), alongside Platelet-Derived Growth Factor (PDGF), Transforming Growth Factor-β (TGF-β), Bone Morphogenetic Proteins (BMP-4, BMP-7), and others. These components are understood to orchestrate beneficial cellular responses, including stimulating cell proliferation and migration, resisting oxidative stress, fostering angiogenesis, and facilitating tissue regeneration and wound healing. On the skin, these actions are theorized to maintain epidermal health, support reparative processes, and contribute to a visibly brighter, clearer, and more radiant complexion.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Formulations containing stem cell conditioned media have demonstrated stability for durations up to 3 years. While a precise optimal pH range for cosmetic stability is not specified, cell lysis for protein extraction from these cells typically occurs at physiological pH (7.4), suggesting this range may be amenable for ingredient integrity.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No dedicated safety assessment by CIR, SCCS, or FDA for this exact cosmetic ingredient has been documented. However, general mesenchymal stem cell conditioned media are often noted for their low immunogenicity when applied topically. Given the immortalized nature of the cells, ongoing regulatory recommendations emphasize the importance of robust quality control, particularly for regenerative medicine applications.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

This ingredient presents compelling theoretical benefits for skin health and rejuvenation stemming from its extensive growth factor profile, however, specific clinical efficacy data and comprehensive cosmetic safety assessments remain insufficient.

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