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Moumoujus

HYSSOPUS OFFICINALIS FLOWER/LEAF/STEM OIL.

Valuable CAS 84603-66-7 / FRAGRANCE, SKIN CONDITIONING

Hyssopus Officinalis Flower/Leaf/Stem Oil is a botanical essential oil prized for its purifying, soothing, and sebum-balancing properties. It offers robust antimicrobial and anti-inflammatory benefits, making it particularly beneficial for maintaining clear and calm skin. Its precise application is key due to specific concentration limits.

Summary

Antimicrobial Anti-inflammatory Antioxidant Astringent Skin conditioning Fragrance Sebum-balancing

Science

Mechanism of Action

This essential oil works through several pathways: it possesses anti-inflammatory capabilities that soothe redness and irritation; its antibacterial action targets acne-causing bacteria, aiding in the prevention of breakouts; and its broader antimicrobial activity inhibits microbial proliferation for a cleaner skin surface. Additionally, it contributes to skin hydration, supports the appearance of minimized pores, and provides antiseptic, disinfecting, and sebum-balancing effects.

Research

Clinical Evidence

Medium confidence
Effective range 0.15–1.5%
Optimal

N/A

Key findings

  1. 01 Demonstrated Minimum Inhibitory Concentration (MIC) against yeast in a liquid medium at 0.15-0.3%.
  2. 02 Exhibited antimycotic activity against 10 different yeast and fungal strains, including Candida albicans, in a range of 15.625-250 μL/mL.
  3. 03 Achieved complete growth inhibition of Aspergillus niger at concentrations of 0.5-1.5% using the agar diffusion method.
  4. 04 Noted to have lower antioxidant activity against DPPH, measuring 1.21 μmol Trolox equivalent (TE)/g.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Conflicts

  • Not recommended for use in high concentrations due to the inherent pinocamphon content, which can be toxic.
  • Avoid formulation for individuals with a history of epileptic symptoms.
  • Contains Methyl Eugenol, which is restricted to a maximum concentration of 0.2% in the final cosmetic product according to EU Council Cosmetic Directive 76/768/EEC Annex III.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Moderate

Hyssopus officinalis is generally regarded as safe in levels typically found in foods, however, its safety profile in cosmetic applications requires more comprehensive study. The oil contains pinocamphon, a compound potentially toxic at elevated concentrations, necessitating careful formulation, particularly avoiding use on individuals susceptible to epileptic episodes. Potential adverse reactions include allergic responses and contact dermatitis. High dosages may induce drowsiness, seizures, and sensory disturbances. Hyssop essential oil naturally contains Methyl Eugenol, which has a regulatory limit of 0.2% in the final cosmetic product as per EU regulations.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hyssopus Officinalis Flower/Leaf/Stem Oil is a valuable ingredient for purifying and soothing formulations, particularly for oily and normal skin types, though its formulation requires precise concentration control due to potential toxicity and irritancy concerns.

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