Science
Mechanism of Action
This extract primarily functions by maintaining skin health and improving its aesthetic quality, rendering it notably softer, smoother, and more supple. It is particularly advantageous for dry or rough skin, assisting in the restoration of moisture and refinement of texture. Its efficacy is rooted in a rich profile of bioactive compounds, including flavonoids, tannins, and saponins. These constituents confer antioxidant activity, demonstrate potential antimicrobial and anti-biofilm properties against bacteria such as *Staphylococcus aureus*, and possess anti-inflammatory attributes. Flavonoids are thought to exert antimicrobial effects through interactions with bacterial cell walls, while phenolic compounds may inhibit enzymatic processes and engage in non-specific interactions with membrane proteins.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A leaf extract (6.25 mg/mL) demonstrated 78.29% anti-biofilm activity against *Staphylococcus aureus*.
- 02 Liquid extract dilutions (1:2, 1:4, 1:8) showed high cell viability (111%, 104%, 82% respectively) in RAW 264.7 cells, indicating a non-toxic profile.
- 03 A hydroalcoholic extract displayed a low toxicity profile with an LC50 of 15076.99 ± 1.66 µg/mL in *Caenorhabditis elegans* (N2 wild-type L4). This study also indicated *in vivo* protection against oxidative stress.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Generally considered safe for topical cosmetic application, exhibiting a low toxicity profile across tested concentrations. However, individuals may experience potential side effects such as skin irritation, allergic reactions, redness, or itching; therefore, a preliminary patch test is recommended before extensive use. Data regarding its topical safety during pregnancy and breastfeeding are currently insufficient, and consultation with a healthcare professional is advised for these populations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hymenaea Courbaril Bark Extract is a valuable botanical, offering significant skin-conditioning and antioxidant benefits with low irritancy and comedogenicity, making it suitable for normal, oily, and dry skin.
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