Science
Mechanism of Action
The primary active component, a soluble polysaccharide designated DL1, demonstrates robust anti-inflammatory action. It functions by significantly suppressing the release of inflammatory cytokines and reactive oxygen species (ROS) in activated macrophages. This effect is achieved through modulation of the mitogen-activated protein kinase (MAPK) pathway, specifically by inhibiting the phosphorylation of p38 and extracellular signal-regulated kinase (ERK).
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Achieved a significant 91.23 ± 0.46% inhibitory effect on bovine serum albumin thermal denaturation by the polysaccharide DL1, demonstrating strong anti-inflammatory potential.
- 02 The polysaccharide DL1 exhibited an IC50 for inhibiting bovine serum albumin denaturation, indicating effective anti-inflammatory activity.
- 03 Polysaccharide DL1 strongly inhibited the release of inflammatory cytokines and reactive oxygen species in lipopolysaccharide-stimulated macrophages, highlighting its anti-inflammatory and antioxidant properties.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The active polysaccharide (DL1) extracted from Hygrophila ringens seeds is soluble in warm water. Soaking the whole seeds in hot water forms a viscous, slimy mass.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) and European Scientific Committee on Consumer Safety (SCCS) have not specifically reviewed Hygrophila Ringens Seed. Its FDA status remains unknown, and no maximum concentration guidelines are established in the provided data.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hygrophila Ringens Seed is a valuable ingredient for targeting inflammation and oxidative stress, particularly beneficial for oily and sensitive skin, though further comprehensive safety data would enhance its application.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources