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HYDROXYPROPYLTRIMONIUM HYDROLYZED WHEAT PROTEIN.

Valuable CAS - / ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

This quaternized wheat protein derivative functions as a versatile skin conditioning agent, providing measurable moisture retention and enhanced barrier support. It helps improve skin texture, contributing to increased firmness and reduced extensibility.

Skin Conditioning

Science

Hydroxypropyltrimonium Hydrolyzed Wheat Protein acts by creating a substantive, protective film on the skin's surface. This film effectively seals in moisture, thereby preventing transepidermal water loss and counteracting dehydration. Beyond surface-level hydration, it physically reinforces the skin's natural barrier, offering protection against environmental irritants. As a quaternized protein, it demonstrates an enhanced affinity for skin, potentially supplying fundamental building blocks and signaling peptides that contribute to cellular defense against oxidative stress and mitigate irritation from cleansing agents.


Research

Medium confidence
Effective range 1–1%
Optimal

1%

Key findings

  1. 01 An in vivo study using a 1% concentration of hydrolyzed wheat protein demonstrated significant improvement in skin firmness, evidenced by a 6.4% decrease in extensibility, indicating a tangible tightening or toning effect.
  2. 02 Clinical evaluations indicated that the incorporation of wheat protein into cleansing formulations notably reduced skin irritation and minimized barrier damage, leading to improved skin hydration and a decrease in transepidermal water loss.

Transparency

Not commonly dusted

No specific data regarding dusting behavior or thresholds for this ingredient is available within the provided research.


The Formula

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

To preserve ingredient integrity, it is crucial to avoid exposure to temperatures exceeding 80°C.

Conflicts

  • Anionic detergents (due to its inherent positive charge)

Safety

CIR Status
Safe with restrictions
Sensitization risk Low

The CIR Expert Panel has concluded that hydrolyzed wheat protein (HWP) is safe for cosmetic use, provided the peptides are formulated to an average molecular weight of 3,500 Da or less (approximately 30 amino acids). Usage is restricted on damaged skin, in products that may contact mucous membranes, or those prone to incidental inhalation. The FDA generally recognizes peptones (hydrolyzed proteins) as safe (GRAS) for direct food use, and this ingredient is listed in the European Commission's CosIng database.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

This quaternized wheat protein is a valuable ingredient for enhancing skin hydration, supporting barrier function, and improving firmness, particularly beneficial in formulations designed for textural improvements and reducing cleanser-induced irritation.


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