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HYDROXYPROPYLTRIMONIUM HYDROLYZED KERATIN.

Valuable CAS - / ANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING

A cationized derivative of hydrolyzed keratin, this ingredient acts as a sophisticated skin conditioning agent. It actively preserves moisture, enhances skin softness, and fortifies the crucial skin barrier for improved hydration and resilience.

Summary

Skin Conditioning Hair Conditioning Antistatic Moisture Preservation Barrier Reinforcement

Science

Mechanism of Action

HYDROXYPROPYLTRIMONIUM HYDROLYZED KERATIN possesses a positive charge, enabling it to adhere effectively to the negatively charged, often compromised, surfaces of the skin. This substantivity allows it to function as a conditioning agent, forming a protective layer that locks in moisture, contributes to a smooth skin texture, and reinforces the skin's natural barrier. The added hydroxypropyl group further augments its hydrating properties and improves its solubility for optimal formulation.

Research

Clinical Evidence

Medium confidence
Effective range 3–25%
Optimal

N/A

Key findings

  1. 01 In an efficacy study, a hydrolyzed keratin peptide (molecular weight <1000 Da) significantly enhanced skin hydration, improved elasticity, and strengthened the skin's barrier integrity upon topical application.
  2. 02 An efficacy assessment of hydrolyzed keratin at 3% concentration in a hand cream formulation demonstrated no adverse effects.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 7.5
0 7 14

Stability

This ingredient exhibits good stability within a pH range of 5.5 to 7.5. Its cationic modification enhances its substantivity and stability across typical cosmetic pH levels, ensuring optimal performance.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
25%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed keratin-derived ingredients, including this compound's base (Hydrolyzed Keratin), safe for cosmetic use within current industry practices and concentrations. Human studies indicate no irritation at concentrations up to 25%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Hydroxypropyltrimonium Hydrolyzed Keratin is a valuable skin conditioning agent, proven safe up to 25%, that effectively hydrates, smooths, and reinforces the skin barrier across all skin types.

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