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HYDROXYMETHOXYPHENYL PROPYLMETHYLMETHOXYBENZOFURAN.

Questionable CAS 51267-48-2 / SKIN CONDITIONING

This complex organic compound, also recognized by its trade name Sym3D, presents multifaceted benefits for skin. It is primarily noted for its potential to enhance lip volume and diminish signs of aging, alongside providing antioxidant protection and improving skin hydration.

Moisturizing Anti-oxidation Anti-aging Lip-plumping Skin conditioning

Science

As Sym3D, this ingredient operates by influencing the underlying skin structure, specifically increasing both the number and size of adipocytes (fat cells). This action facilitates enhanced lipid uptake and accumulation within these cells, contributing to a plumping effect, particularly beneficial for lip volume, and reducing the appearance of lines and wrinkles. Furthermore, it demonstrates antioxidative activity and supports the skin's natural production of hyaluronic acid.


Research

Medium confidence
Effective range N/A
Optimal

0.25%

Key findings

  1. 01 A manufacturer-conducted clinical study on 44 female volunteers reported a 6% increase in lip volume over 28 days with twice-daily application.

Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk High

The Cosmetic Ingredient Review (CIR) has not yet assessed this ingredient. Comprehensive toxicity data, including oral, dermal, and inhalation, remain undetermined. No Globally Harmonized System (GHS) hazard classification has been established. INCIDecoder rates its irritancy as high.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy High
Comedogenicity Low

Our Assessment

Questionable

While demonstrating promising efficacy in lip plumping and anti-aging, the high reported irritancy and the absence of comprehensive safety and toxicology data necessitate extreme caution and further independent evaluation before widespread use in precision skincare.


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