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Moumoujus

HYDROXYMETHOXYIODOBENZYL GLYCOLAMIDE PELARGONATE.

Valuable CAS 2225980-46-9 / ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

HYDROXYMETHOXYIODOBENZYL GLYCOLAMIDE PELARGONATE, also known as Calmapsin, is a advanced neurocosmetic ingredient engineered for sensitive and reactive skin. It precisely targets the root causes of discomfort, delivering rapid itch reduction, enhanced moisturization, and significant antioxidant protection.

Summary

skin conditioning antioxidant skin protecting anti-itch calming anti-inflammatory barrier support

Science

Mechanism of Action

As a novel capsaicinoid and TRPV1 antagonist, HYDROXYMETHOXYIODOBENZYL GLYCOLAMIDE PELARGONATE operates by inhibiting the activation of sensory neurons, thereby effectively mitigating itch sensations directly at their origin. This ingredient exerts a comprehensive effect on both sensory neurons and skin cells, manifesting calming and antioxidant properties, reducing neuronal hyperreactivity, diminishing inflammation and redness, and bolstering the skin's natural barrier against environmental aggressors.

Research

Clinical Evidence

Medium confidence
Effective range 0.025–0.025%
Optimal

0.025%

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability was found in the available data.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the manufacturer asserts the ingredient's safety, comprehensive safety assessments by regulatory bodies such as CIR, SCCS, or FDA were not identified in the provided research.

Your Skin

Skin Compatibility

No Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This ingredient is a valuable asset for formulations targeting sensitive, dry, or irritated skin, offering proven immediate itch relief and long-term calming and protective benefits.

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