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HYDROXYLAUROYL PHYTOSPHINGOSINE.

Valuable CAS - / HAIR CONDITIONING, SKIN CONDITIONING

Hydroxylauroyl Phytosphingosine is a skin-identical ceramide, a crucial lipid naturally present in the skin's stratum corneum. It is designed to reinforce the skin's inherent moisture barrier, effectively reducing transepidermal water loss and enhancing deep hydration.

Barrier Reinforcer Hydrator Antimicrobial Anti-inflammatory Cell Communicator Natural Moisturizing Factor (NMF) Booster

Science

This ceramide operates by integrating into the skin's natural lipid matrix, thereby strengthening the barrier function and minimizing moisture evaporation. Its unique phytosphingosine backbone imparts additional antimicrobial and anti-inflammatory properties, contributing to the skin's innate defense system and potentially assisting in acne management. As a cell-communicating ingredient, it also stimulates filaggrin biosynthesis and degradation, which leads to the formation of Natural Moisturizing Factors (NMFs) vital for maintaining optimal skin hydration.


Research

Medium confidence
Effective range 0.02–0.1%
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Hydroxylauroyl Phytosphingosine, like other ceramides and phytosphingosines, exhibits inherently low solubility in both oil and water. Optimal and stable incorporation into formulations typically requires advanced techniques, such as nanoemulsions, leveraging both hydrophilic and lipophilic surfactants.


Safety

CIR Status
Safe as used
Max tested
0.1%
Sensitization risk Low

While Hydroxylauroyl Phytosphingosine specifically lacks individual CIR assessment, closely related ingredients like Phytosphingosine and Hydroxycapryloyl Phytosphingosine have been evaluated. Phytosphingosine is deemed safe for topical use up to 0.1% in dermal cosmetic products, with a recommendation against use in products intended for the eye area. These related ceramides are generally well-tolerated by most skin types, suggesting a low sensitization risk for this ceramide.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Hydroxylauroyl Phytosphingosine is a valuable skin-identical ceramide, offering comprehensive barrier reinforcement, enhanced hydration, and additional antimicrobial and anti-inflammatory benefits, making it crucial for maintaining optimal skin health and function.


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