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HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCL.

Avoid CAS 135043-63-9 / HAIR DYEING

HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCL is an aromatic amine derivative primarily utilized as a colorless precursor in oxidative hair dyeing systems. It initiates chemical reactions within the hair fiber to form permanent dyes, and is not associated with direct skincare benefits.

Summary

Hair Dye Precursor

Science

Mechanism of Action

This compound functions as a hair dyeing agent by acting as a colorless precursor, specifically a developer or coupler, within oxidative hair coloring systems. Upon activation with an oxidizing agent, it undergoes a chemical reaction inside the hair fiber to produce colored molecules, resulting in permanent hair coloration. It lacks a defined mechanism of action relevant to skin physiology.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCL is a specialized ingredient for hair dyeing and is not typically employed or 'dusted' as an active component in precision skincare formulations, primarily due to its specific chemical reactivity and safety profile for skin.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability has been precisely determined for this exact ingredient, although related p-aminophenol exhibited stability over a studied period. As an oxidative hair dye precursor, it is inherently designed to react with oxidizing agents during the hair coloring process. Exposure to strong heat leads to decomposition and the emission of toxic fumes.

Conflicts

  • Oxidizing agents (during storage, to prevent premature reaction)
  • Nitrosating substances (for related secondary amines, to mitigate nitrosamine formation)
  • Strong heat (induces decomposition and toxic fume release)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk High

HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCL is classified with GHS hazard statements H302 (Harmful if swallowed) and H317 (May cause an allergic skin reaction), categorizing it as Acute toxicity - category 4 and Skin sensitisation - category 1. Its use is regulated and restricted specifically to hair dye products. The FDA provides exemptions for 'coal tar hair dyes' containing this ingredient from certain provisions, provided product labels include necessary caution statements and patch test instructions.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

HYDROXYETHYLAMINOMETHYL-P-AMINOPHENOL HCL is primarily a hair dye precursor with no demonstrated efficacy for skin and carries a high risk of skin sensitization, rendering it unsuitable for integration into precision skincare formulations.

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