Science
Mechanism of Action
As a cationic polymer, HYDROXYETHYL PEI-1500 is characterized by multiple positively charged amine groups along its molecular chain. This intrinsic charge enables it to form strong interactions with negatively charged biological surfaces, such as hair keratin and the skin's surface. These interactions facilitate cleansing by attracting impurities, provide conditioning effects, and contribute to film-forming properties that can enhance barrier function.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Recommended usage rates in hair care products typically range from 0.05% to 0.5%.
- 02 Demonstrates antibacterial efficacy with a Minimum Inhibitory Concentration (MIC) of 16 ppm against Staphylococcus aureus and 31 ppm against Pseudomonas aeruginosa.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient exhibits robust stability across a wide pH range, specifically between 3.0 and 10.0. While heat-tolerant, it is crucial to avoid exposure to temperatures exceeding 80°C during formulation to maintain its integrity.
Conflicts
- citric acid
Safety
Safety Profile
HYDROXYETHYL PEI-1500 is generally considered non-irritating. Studies on a structurally similar compound, Poly(2-hydroxyethyl ethyleneimine), indicate low toxicity in human dermal skin fibroblast cells. The maximum recommended concentration for use in cosmetic formulations is up to 1%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
HYDROXYETHYL PEI-1500 is a valuable multi-functional cationic polymer, offering effective cleansing, conditioning, and antimicrobial benefits with low irritancy, suitable for all skin types within appropriate concentrations.
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References
Sources