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HYDROXYETHYL CHITOSAN.

Valuable CAS 39280-86-9 / FILM FORMING, VISCOSITY CONTROLLING

Hydroxyethyl Chitosan is a biocompatible, water-soluble derivative of chitosan engineered for enhanced hydration and protective film formation on the skin. It excels in moisture retention, contributing to a stable skin barrier while exhibiting inherent antibacterial properties.

Moisturizer Film Former Viscosity Controlling Antimicrobial Wound Healing Support

Science

Hydroxyethyl Chitosan functions by creating a stable, permeable film on the skin's surface, which effectively seals in moisture and improves hydration levels. This protective layer not only retains essential water but also contributes to the skin's overall texture and stability. Furthermore, it possesses intrinsic antibacterial properties and demonstrates potential in supporting wound healing through exudate absorption and reduction of inflammatory mediators.


Research

Medium confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6.5 – 8.5
0 7 14

Stability

Hydroxyethyl Chitosan is designed for enhanced water solubility and exhibits stable hydration within formulations, maintaining a mild and consistent nature. While its base polymer, chitosan, favors acidic conditions, hydroxyethylation broadens its functional pH range to 6.5-8.5 (for a 1% solution).

Conflicts

  • Divalent cations (e.g., dicalcium phosphate dihydrate, calcium carbonate, magnesium stearate) may form coordination complexes with the amino groups, potentially impacting stability. This is extrapolated from general chitosan behavior.

Safety

CIR Status
Not reviewed
Sensitization risk Low

Hydroxyethyl Chitosan is characterized by its biocompatibility, non-toxicity, and rapid biodegradability. Currently, there is no specific safety assessment from the Cosmetic Ingredient Review (CIR) or SCCS for its cosmetic use, nor direct FDA status as a cosmetic ingredient.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

Hydroxyethyl Chitosan is a valuable multi-functional ingredient, offering significant hydration, protective film-forming, and potential antimicrobial and wound-healing benefits for a wide range of skin types.


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