Science
Mechanism of Action
This ingredient functions as a humectant, drawing and holding moisture within the skin, thereby enhancing its water-holding capacity and improving moisturization. By reinforcing skin barrier integrity, it contributes to a smoother feel and improved overall appearance. Furthermore, low molecular weight keratin hydrolysates possess the potential to stimulate cellular mechanisms crucial for wound healing, fostering skin regeneration and repair through the promotion of fibroblast and keratinocyte activity, and may even penetrate the skin.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 When incorporated into a hand cream, no adverse effects were observed in an efficacy study.
- 02 Low molecular weight (<1000 Da) hydrolyzed keratin peptide from wool, in both aqueous and liposomal forms, significantly enhanced hydration and elasticity, while also strengthening skin barrier integrity in long-term in vivo studies.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal pH for keratin proteins typically spans 5.0 to 5.8, or alternatively 6.0 to 7.5. Formulators should note that higher molecular weight (>3000 Da) hydrolyzed keratins offer better emulsifying and thickening properties, whereas lower molecular weight (<1000 Da) versions may not be suitable for emulsion creation. Direct addition to certain products, such as conditioners, can lead to precipitation, necessitating specific formulation strategies.
Conflicts
- May precipitate if simply added to certain conditioners.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has affirmed Hydrolyzed Keratin, including that derived from sheep wool, as safe under current usage conditions and concentrations. It demonstrated non-irritating properties at 100% in in vitro tests and minimal to no irritation in neat Draize rabbit studies. Patch tests showed no sensitization up to 5% concentration, though slight ocular irritation was observed at 10%. A rare allergic reaction has been documented in relation to a hair conditioner containing hydrolyzed keratin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Hydrolyzed Wool is a valuable ingredient for comprehensive skin care, offering proven benefits in moisturization, elasticity, and barrier support across all skin types with a favorable safety profile.
Related
Similar Ingredients
Finding similar ingredients…